Ultra-efficient frequency comb generation in AlGaAs-on-insulator microresonators

Recent advances in nonlinear optics have revolutionized integrated photonics, providing on-chip solutions to a wide range of new applications. Currently, state of the art integrated nonlinear photonic devices are mainly based on dielectric material platforms, such as Si₃N₄ and SiO₂. While semiconductor materials feature much higher nonlinear coefficients and convenience in active integration, they have suffered from high waveguide losses that prevent the realization of efficient nonlinear processes on-chip. Here, we challenge this status quo and demonstrate a low loss AlGaAs-on-insulator platform with anomalous dispersion and quality (Q) factors beyond 1.5 × 10⁶. Such a high quality factor, combined with high nonlinear coefficient and small mode volume, enabled us to demonstrate a Kerr frequency comb threshold of only ∼36 µW in a resonator with a 1 THz free spectral range, ∼100 times lower compared to that in previous semiconductor platforms. Moreover, combs with broad spans (>250 nm) have been generated with a pump power of ∼300 µW, which is lower than the threshold power of state-of the-art dielectric micro combs. A soliton-step transition has also been observed for the first time in an AlGaAs resonator

Transocular Entry of Seasonal Influenza-Attenuated Virus Aerosols and the Efficacy of N95 Respirators, Surgical Masks, and Eye Protection in Humans

Background. The efficacy of barrier precautions to prevent influenza transmission is unknown. Methods. Twenty-eight participants were exposed to monodispersed live attenuated influenza vaccine (LAIV) particles (4.9 lm) in 6 groups: group 1, no precautions; group 2, ocular exposure only; group 3, surgical mask without eye protection; group 4, surgical mask with eye protection; group 5, fit-tested N95 respirator without eye protection; and group 6, fit-tested N95 respirator with eye protection. Influenza was detected by reversetranscription polymerase chain reaction (RT-PCR) and culture in nasal washes. Exact 95% confidence intervals (CIs) were calculated. Results. Influenza was detected in 4 of 4 participants in group 1 (95% CI, 0-.60), 3 of 4 in group 2 (95% CI, .006-.806]), 5 of 5 in group 3 (95% CI, 0-.522), 5 of 5 in group 4, (95% CI, 0-.522), 3 of 5 in group 5 (95% CI, .053-.853), and 1 of 5 in group 6 (95% CI, .05-.72). RT-PCR revealed significant differences between group 1 and all other groups except group 3. Conclusions. Transocular transmission of LAIV occured in most participants suggesting the necessity of eye protection. An N95 respirator provided the best guard further enhanced by eye protection

Drought Prediction for Socio-Cultural Stability Project

The primary objective of this project is to answer the question: "Can existing, linked infrastructures be used to predict the onset of drought months in advance?" Based on our work, the answer to this question is "yes" with the qualifiers that skill depends on both lead-time and location, and especially with the associated teleconnections (e.g., ENSO, Indian Ocean Dipole) active in a given region season. As part of this work, we successfully developed a prototype drought early warning system based on existing/mature NASA Earth science components including the Goddard Earth Observing System Data Assimilation System Version 5 (GEOS-5) forecasting model, the Land Information System (LIS) land data assimilation software framework, the Catchment Land Surface Model (CLSM), remotely sensed terrestrial water storage from the Gravity Recovery and Climate Experiment (GRACE) and remotely sensed soil moisture products from the Aqua/Advanced Microwave Scanning Radiometer - EOS (AMSR-E). We focused on a single drought year - 2011 - during which major agricultural droughts occurred with devastating impacts in the Texas-Mexico region of North America (TEXMEX) and the Horn of Africa (HOA). Our results demonstrate that GEOS-5 precipitation forecasts show skill globally at 1-month lead, and can show up to 3 months skill regionally in the TEXMEX and HOA areas. Our results also demonstrate that the CLSM soil moisture percentiles are a goof indicator of drought, as compared to the North American Drought Monitor of TEXMEX and a combination of Famine Early Warning Systems Network (FEWS NET) data and Moderate Resolution Imaging Spectrometer (MODIS)'s Normalizing Difference Vegetation Index (NDVI) anomalies over HOA. The data assimilation experiments produced mixed results. GRACE terrestrial water storage (TWS) assimilation was found to significantly improve soil moisture and evapotransportation, as well as drought monitoring via soil moisture percentiles, while AMSR-E soil moisture assimilation produced marginal benefits. We carried out 1-3 month lead-time forecast experiments using GEOS-5 forecasts as input to LIS/CLSM. Based on these forecast experiments, we find that the expected skill in GEOS-5 forecasts from 1-3 months is present in the soil moisture percentiles used to indicate drought. In the case of the HOA drought, the failure of the long rains in April appears in the February 1, March 1 and April 1 initialized forecasts, suggesting that for this case, drought forecasting would have provided some advance warning about the drought conditions observed in 2011. Three key recommendations for follow-up work include: (1) carry out a comprehensive analysis of droughts observed over the entire period of record for GEOS-5 forecasts; (2) continue to analyze the GEOS-5 forecasts in HOA stratifying by anomalies in long and short rains; and (3) continue to include GRACE TWS, Soil Moisture/Ocean Salinity (SMOS) and the upcoming NASA Soil Moisture Active/Passive (SMAP) soil moisture products in a routine activity building on this prototype to further quantify the benefits for drought assessment and prediction

JPL Space Telecommunications Radio System Operating Environment

A flight-qualified implementation of a Software Defined Radio (SDR) Operating Environment for the JPL-SDR built for the CoNNeCT Project has been developed. It is compliant with the NASA Space Telecommunications Radio System (STRS) Architecture Standard, and provides the software infrastructure for STRS compliant waveform applications. This software provides a standards-compliant abstracted view of the JPL-SDR hardware platform. It uses industry standard POSIX interfaces for most functions, as well as exposing the STRS API (Application Programming In terface) required by the standard. This software includes a standardized interface for IP components instantiated within a Xilinx FPGA (Field Programmable Gate Array). The software provides a standardized abstracted interface to platform resources such as data converters, file system, etc., which can be used by STRS standards conformant waveform applications. It provides a generic SDR operating environment with a much smaller resource footprint than similar products such as SCA (Software Communications Architecture) compliant implementations, or the DoD Joint Tactical Radio Systems (JTRS)

New Five Dimensional Black Holes Classified by Horizon Geometry, and a Bianchi VI Braneworld

We introduce two new families of solutions to the vacuum Einstein equations with negative cosmological constant in 5 dimensions. These solutions are static black holes whose horizons are modelled on the 3-geometries nilgeometry and solvegeometry. Thus the horizons (and the exterior spacetimes) can be foliated by compact 3-manifolds that are neither spherical, toroidal, hyperbolic, nor product manifolds, and therefore are of a topological type not previously encountered in black hole solutions. As an application, we use the solvegeometry solutions to construct Bianchi VI$_{-1}$ braneworld cosmologies.Comment: LaTeX, 20 pages, 2 figures Typographical errors corrected, and references to printed matter added in favour of preprints where possibl

Murine Anti-vaccinia Virus D8 Antibodies Target Different Epitopes and Differ in Their Ability to Block D8 Binding to CS-E

The IMV envelope protein D8 is an adhesion molecule and a major immunodominant antigen of vaccinia virus (VACV). Here we identified the optimal D8 ligand to be chondroitin sulfate E (CS-E). CS-E is characterized by a disaccharide moiety with two sulfated hydroxyl groups at positions 4′ and 6′ of GalNAc. To study the role of antibodies in preventing D8 adhesion to CS-E, we have used a panel of murine monoclonal antibodies, and tested their ability to compete with CS-E for D8 binding. Among four antibody specificity groups, MAbs of one group (group IV) fully abrogated CS-E binding, while MAbs of a second group (group III) displayed widely varying levels of CS-E blocking. Using EM, we identified the binding site for each antibody specificity group on D8. Recombinant D8 forms a hexameric arrangement, mediated by self-association of a small C-terminal domain of D8. We propose a model in which D8 oligomerization on the IMV would allow VACV to adhere to heterogeneous population of CS, including CS-C and potentially CS-A, while overall increasing binding efficiency to CS-E

Ultra-efficient frequency comb generation in AlGaAs-on-insulator microresonators

We demonstrated ultra-efficient frequency comb generation in AlGaAs-on-insulator ring resonators that have a quality factor beyond 1.5*10⁶. The threshold power is as low as 36 µW

Ultra-efficient frequency comb generation in AlGaAs-on-insulator microresonators

Recent advances in nonlinear optics have revolutionized integrated photonics, providing on-chip solutions to a wide range of new applications. Currently, state of the art integrated nonlinear photonic devices are mainly based on dielectric material platforms, such as Si₃N₄ and SiO₂. While semiconductor materials feature much higher nonlinear coefficients and convenience in active integration, they have suffered from high waveguide losses that prevent the realization of efficient nonlinear processes on-chip. Here, we challenge this status quo and demonstrate a low loss AlGaAs-on-insulator platform with anomalous dispersion and quality (Q) factors beyond 1.5 × 10⁶. Such a high quality factor, combined with high nonlinear coefficient and small mode volume, enabled us to demonstrate a Kerr frequency comb threshold of only ∼36 µW in a resonator with a 1 THz free spectral range, ∼100 times lower compared to that in previous semiconductor platforms. Moreover, combs with broad spans (>250 nm) have been generated with a pump power of ∼300 µW, which is lower than the threshold power of state-of the-art dielectric micro combs. A soliton-step transition has also been observed for the first time in an AlGaAs resonator